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AI in prior authorization offers theoretical efficiency but faces strong criticism for potentially increasing wrongful denials and patient harm. While programs like WISeR aim to cut waste, concerns persist about transparency, profit incentives, and the automation of an already flawed system, suggesting a mixed prognosis.

CAR T cell therapy, a revolutionary cancer treatment, is showing transformative potential for severe autoimmune diseases. This review covers its mechanism, promising patient outcomes, significant acute and long-term risks, and high costs, alongside efforts to make it safer and more accessible.